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Jérôme Dejeu

Département MN2S
équipe Nano2BIO

ENSMM

Courriel :: jerome.dejeu2 [at] femto-st.fr
Adresse :: TEMIS
15B avenue des Montboucons
25030 BESANCON cedex

Domaines de recherche
Interactions biomoléculaires, physico-chimie, fonctionnalisation de surface

Habilitation à diriger des recherches en 2017 Caractérisations physico-chimiques des interactions (bio-)moléculaires

Responsabilités
Coordinateur de l’axe Etude Biophysic des Interactions Biomoléculaires de l'équipe I2BM de DCM grenoble (2016-2023)
Coordinateur scientifique du plateau Caractérisation des Interactions de la plate-forme NANOBIO- ICMG (UAR 2607) (Grenoble 2014-2023)
Vice-président de la SCF Rhône-Alpes (2020-2022)

Publication
L'ensemble des mes publications sont disponibles à l'adresse suivante : https://publons.com/researcher/2671355/jerome-dejeu/publications/

Mon parcours :
Depuis 2021 : En délégation à l'Université de Franche Comté (Institut Femto-ST, département MN2S, équipe Nano2BIO)
Depuis 2012 : Enseignant Chercheur à l'Université Grenoble Alpes (Département de Chimie Moléculaire, équipe I2BM)

2010-2012 : Chercheur contractuel au sein du département AS2M de l’Institut FEMTO-ST
Fonctionnalisation et caractérisation (AFM, mesure de Force d’adhésion et de friction) de surface de MEMS (Micro-Electro-Mechanical-System) pour solidariser des objet sur une surface
2008-2010 : Post Doctorat au sein du département MN2S et AS2M de l’Institut FEMTO-ST
Fonctionnalisation et caractérisation (AFM, mesure de Force d’adhésion et de friction) de surface de MEMS (Micro-Electro-Mechanical-System) pour fiabiliser la préhension, le lâcher de micro-objets par une micropince
2004-2007 : Thèse de Doctorat de Chimie Physique, Université de Franche-Comté sous la directions des Prs Alain Foissy et François Membrey.
Titre : Films de deux polymères auto-assemblés : chlorhydrate de polyallylamine (PAH) et polystyrène sulfonate de sodium (PSS) ; Mécanisme de croissance et stabilité
2002-2003 : DEA de Chimie Physique, Université de Franche-Comté
2001-2002 : Maîtrise de Chimie, Université de Franche-Comté
2000-2001 : Licence de Chimie, Université de Franche-Comté
1998-2000 : DEUG en Science de la matière, option Chimie,Université de Franche-Comté, Mention Bien
1997-1998 : Baccalauréat Scientifique, Lycée du Près Saint Sauveur (Saint Claude, Jura)

Publications de Jérôme Dejeu

Voir toutes les publications (29)2025 (1)2024 (7)2023 (7)2022 (3)2021 (1)2013 (2)2012 (3)2010 (5)

2025 (1)

article - Structural insights into the interaction between testis-specific Y-encoded-like protein 5 and ubiquitin-specific protease 7
Protein Science (Volume 34, Issue (5), apr 2025, Pages :70116 (16))
Ancia, Marine | Wahni, Khadija | Chakrowf, Joudy | El Aakchioui, Asia | Claude, Eloïse | De Lhoneux, Guillaume | Liberelle, Maxime | Janvier, Steven | Baranova, Ekaterina | Malo Pueyo, Julia | Jijon Vergara, Ariana | Papadopoulos, Nicolas | Balty, Clémence | Dejeu, Jérôme | Decottignies, Anabelle | Messens, Joris | Frédérick, Raphaël
pdf | doi

2024 (7)

inproceedings - Non specificity of I-motif ligands and I-Mab antiboby demonstrated by Bio-Layer Interferometry (BLI) and circular dichroïsm (CD)
Quadruplexes Made in France (2024) / Palaiseau, France (2024)
Boissieras, Joseph | Bonnet, Hugues | Susanto, Maria Fidelia | Gomez, Dennis | Riou, Jean-François | Granhzam, Anton | Defrancq, Eric | Dejeu, Jérôme
bibtex@inproceedings{75262e36-9d01-49e4-adee-fbc34f79325a, title = {Non specificity of I-motif ligands and I-Mab antiboby demonstrated by Bio-Layer Interferometry (BLI) and circular dichro\"ism (CD)}, author = {Boissieras, Joseph and Bonnet, Hugues and Susanto, Maria Fidelia and Gomez, Dennis and Riou, Jean-Fran\c{c}ois and Granhzam, Anton and Defrancq, Eric and Dejeu, J\'er\^ome}, year = {2024}, address = {Palaiseau, France}, booktitle = {Quadruplexes Made in France (2024)}, editor = {}, month = {nov} }
inproceedings - Discovery of novel G4 Binding peptidic derivatives using DNA encoded chemical libraries
Quadruplexes Made in France (2024) / Palaiseau, France (2024)
Trincas, Massimo | Degotte, G. | Rieber, P. | Si, Y. | Van Wesemael, C. | Lartia, Rémy | Bonnet, Hugues | Dejeu, Jérôme | Jamet, H. | Ducongé, F. | Lavergne, Thomas
bibtex@inproceedings{2519fd71-f11d-4da6-a825-ec0e0d235d83, title = {Discovery of novel G4 Binding peptidic derivatives using DNA encoded chemical libraries }, author = {Trincas, Massimo and Degotte, G. and Rieber, P. and Si, Y. and Van Wesemael, C. and Lartia, R\'emy and Bonnet, Hugues and Dejeu, J\'er\^ome and Jamet, H. and Ducong\'e, F. and Lavergne, Thomas}, year = {2024}, address = {Palaiseau, France}, booktitle = {Quadruplexes Made in France (2024)}, editor = {}, month = {nov} }
misc - La structure i-motif de l’ADN existe-t-elle vraiment dans la cellule ?
https://www.inc.cnrs.fr/fr/cnrsinfo/la-structure-i-motif-de-ladn-existe-t-elle-vraiment-dans-la-cellule (oct 2024)
Defrancq, Eric | Dejeu, Jérôme | Granzhan, Anton
bibtex@misc{b4139512-38f3-4223-a6c2-118758d4ec07, title = {La structure i-motif de l'ADN existe-t-elle vraiment dans la cellule ?}, author = {Defrancq, Eric and Dejeu, J\'er\^ome and Granzhan, Anton}, year = {2024}, editor = {b4139512-38f3-4223-a6c2-118758d4ec07-editor.pdf}, month = {oct}, url = {https://publiweb.femto-st.fr/tntnet/entries/20835/documents/author/data}, doi = {} }
article - iMab antibody binds single-stranded cytosine-rich sequences and unfolds DNA i-motif
Nucleic Acids Research (Volume 52, Issue (14), aug 2024, Pages :8052–8062)
Boissieras, Joseph | Bonnet, Hugues | Susanto, Maria Fidelia | Gomez, Dennis | Defrancq, Eric | Granzhan, Anton | Dejeu, Jérôme
pdf | doi
inproceedings - Non specificity of I-motif ligands and I-Mab antiboby demonstrated by Bio-Layer Interferometry (BLI) and circular dichroïsm (CD)
4ème journée GDR ChemBio (GDR ChemBio 2024) / Bordeaux, France (2024)
Boissieras, Joseph | Bonnet, Hugues | Susanto, Maria Fidelia | Gomez, Dennis | Riou, Jean-François | Granhzam, Anton | Defrancq, Eric | Dejeu, Jérôme
bibtex@inproceedings{5e828940-657d-4b98-91a0-87b7849f812a, title = {Non specificity of I-motif ligands and I-Mab antiboby demonstrated by Bio-Layer Interferometry (BLI) and circular dichro\"ism (CD)}, author = {Boissieras, Joseph and Bonnet, Hugues and Susanto, Maria Fidelia and Gomez, Dennis and Riou, Jean-Fran\c{c}ois and Granhzam, Anton and Defrancq, Eric and Dejeu, J\'er\^ome}, year = {2024}, address = {Bordeaux, France}, booktitle = {4\`eme journ\'ee GDR ChemBio (GDR ChemBio 2024)}, editor = {5e828940-657d-4b98-91a0-87b7849f812a-editor.pdf}, month = {jun} }
inproceedings - Non specificity of I-motif ligands and antibody demonstrated by Bio-Layer Interferometry (BLI)
3rd Molecular-scale biophysics research infrastructure (MOSBRI SCIENTIFIC CONFERENCE 2024) / LJUBLJANA, Slovenia (2024)
Bonnet, Hugues | Susanto, Maria Fidelia | Boissieras, Joseph | Gomez, Dennis | Riou, Jean-François | Granhzam, Anton | Defrancq, Eric | Dejeu, Jérôme
pdf | bibtex@inproceedings{5ddfcb42-f2f2-46c0-b200-a1f8e002f735, title = {Non specificity of I-motif ligands and antibody demonstrated by Bio-Layer Interferometry (BLI)}, author = {Bonnet, Hugues and Susanto, Maria Fidelia and Boissieras, Joseph and Gomez, Dennis and Riou, Jean-Fran\c{c}ois and Granhzam, Anton and Defrancq, Eric and Dejeu, J\'er\^ome}, year = {2024}, address = {LJUBLJANA, Slovenia}, booktitle = {3rd Molecular-scale biophysics research infrastructure (MOSBRI SCIENTIFIC CONFERENCE 2024)}, editor = {}, month = {jun}, url = {https://publiweb.femto-st.fr/tntnet/entries/20624/documents/author/data} }
article - Systematic Evaluation of Benchmark G4 Probes and G4 Clinical Drugs using three Biophysical Methods: A Guideline to Evaluate Rapidly G4-Binding Affinity
ChemBioChem (Volume 25, Issue (12), apr 2024, Pages :e202400210 (14))
Laigre, Eugénie | Bonnet, Hugues | Beauvineau , Claire | Lavergne, Thomas | Verga , Daniela | Defrancq, Eric | Dejeu, Jérôme | Teulade-Fichou, Marie-Paule
pdf | doi

2023 (7)

article - Chemical Biology of G-quadruplex and i-motif DNA: use of topologically constrained DNA
Comptes Rendus Chimie (Volume 26, Issue (3), oct 2023, Pages :1 - 14)
Dejeu, Jérôme | Defrancq, Eric
pdf | doi
inproceedings - Bio-Layer Interferometry (BLI): a useful tool to investigate the interactions of i-motif DNA with small molecules and proteins
6ème journée plénière GDR B2I (GDR B2I 2023) / Louvain-La-Neuve, Belgium (2023)
Bonnet, Hugues | Gomez, Dennis | Riou, Jean-François | Granhzam, Anton | Defrancq, Eric | Dejeu, Jérôme
pdf | bibtex@inproceedings{9a3d2e34-8945-4b3a-a183-9604e43988cc, title = {Bio-Layer Interferometry (BLI): a useful tool to investigate the interactions of i-motif DNA with small molecules and proteins}, author = {Bonnet, Hugues and Gomez, Dennis and Riou, Jean-Fran\c{c}ois and Granhzam, Anton and Defrancq, Eric and Dejeu, J\'er\^ome}, year = {2023}, address = {Louvain-La-Neuve, Belgium}, booktitle = {6\`eme journ\'ee pl\'eni\`ere GDR B2I (GDR B2I 2023)}, editor = {}, month = {jun}, url = {https://publiweb.femto-st.fr/tntnet/entries/19865/documents/author/data} }
inproceedings - Biological relevance and targeting of i-motif DNA
3èmes journées GDR ChemBio (GDR ChemBio 2023) / STRASBOURG, France (2023)
Bonnet, Hugues | Gomez, Dennis | Riou, Jean-François | Granhzam, Anton | Defrancq, Eric | Dejeu, Jérôme
pdf | bibtex@inproceedings{c524d468-4ecb-4ecd-a26c-334198dfb559, title = {Biological relevance and targeting of i-motif DNA}, author = {Bonnet, Hugues and Gomez, Dennis and Riou, Jean-Fran\c{c}ois and Granhzam, Anton and Defrancq, Eric and Dejeu, J\'er\^ome}, year = {2023}, address = {STRASBOURG, France}, booktitle = {3\`emes journ\'ees GDR ChemBio (GDR ChemBio 2023)}, editor = {c524d468-4ecb-4ecd-a26c-334198dfb559-editor.pdf}, month = {jun}, url = {https://publiweb.femto-st.fr/tntnet/entries/19866/documents/author/data} }
article - Cell-free expression and characterization of multivalent rhamnose-binding lectins using bio-layer interferometry
Glycobiology (Volume 33, Issue (5), may 2023, Pages :358 - 363)
Warfel , Katherine F | Laigre, Eugénie | Sobol, Sarah E | Gillon, Emilie | Varrot, Annabelle | Renaudet, Olivier | Dejeu, Jérôme | Jewett, Michael C | Imberty, Anne
pdf | doi
article - Repulsive Force for Micro- and Nano-Non-Contact Manipulation
Applied Sciences (Volume 13, Issue (6), mar 2023, Pages :3886 (14))
Cot, Amélie | Rougeot, Patrick | Lakard, Sophie | Gauthier, Michaël | Dejeu, Jérôme
pdf | doi
article - Novel Synthesis of IMC-48 and Affinity Evaluation with Different i-Motif DNA Sequences
Molecules (Volume 28, Issue (2), jan 2023, Pages :28020682 (13))
Berthiol, Florian | Boissieras, Joseph | Bonnet, Hugues | Pierrot, Marie | Philouze, Christian | Poisson, Jean-François | Granzhan, Anton | Defrancq, Eric | Dejeu, Jérôme
pdf | doi
article - Luminescent Ruthenium(II) Complexes Used for the Detection of 8-Oxoguanine in the Human Telomeric Sequence
Bioconjugate Chemistry (Volume 34, Issue (1), jan 2023, Pages :414 - 421)
Gillard, Martin | Bonnet, Hugues | Lartia, Rémy | Yacoub, Hiba | Dejeu, Jérôme | Defrancq, Eric | Elias, Benjamin
pdf | doi

2022 (3)

article - Conformational transition in SPR experiments: impact of spacer length, immobilization mode and aptamer density on signal sign and amplitude
Analyst (Volume 19, Issue (147), aug 2022, Pages :4197 - 4205)
Pons, Marina | Perenon, Marine | Bonnet, Hugues | Gillon, Emilie | Vallée, Celio | Coche-Guérante, Liliane | Defrancq, Eric | Spinelli, Nicolas | Van der Heyden, Angeline | Dejeu, Jérôme
pdf | doi
article - Characterization of the interaction of multivalent glycosylated ligands with bacterial lectins by BioLayer Interferometry
Glycobiology (Volume 32, Issue (10), jul 2022, Pages :886 - 896)
Picault, Léo | Laigre, Eugénie | Gillon, Emilie | Tiertant, Claire | Renaudet, Olivier | Imberty, Anne | Goyard, David | Dejeu, Jérôme
pdf | doi
article - Assessment of presumed small-molecule ligands of telomeric i-DNA by biolayer interferometry (BLI)
Chemical Communications (Volume 58, apr 2022, Pages :5116 - 5119)
Bonnet, Hugues | Morel, Maéva | Devaux, Alexandre | Boissieras, Joseph | Granzhan, Anton | Elias, Benjamin | Lavergne, Thomas | Dejeu, Jérôme | Defrancq, Eric
pdf | doi

2021 (1)

article - Development of new sticky and conducting polymer surfaces for MEMS applications
Synthetic Metals (Volume 276, jun 2021, Pages :116757)
Dejeu, Jérôme | Cot, Amélie | Rougeot, Patrick | Lakard, Boris | Lakard, Sophie | Gauthier, Michaël
pdf | doi

2013 (2)

inproceedings - Modeling of electrostatic forces induced by chemical surface functionalisation for microrobotics applications
IEEE/RSJ International Conference on Intelligent Robots and Systems, IROS'13. / Tokyo, Japan (2013, Pages pages 2065 - 2070)
Cot, Amélie | Dejeu, Jérôme | Lakard, Sophie | Rougeot, Patrick | Gauthier, Michaël
pdf | doi | bibtex@inproceedings{c510e60a-48a6-4a8d-8bfc-870f389be089, title = {Modeling of electrostatic forces induced by chemical surface functionalisation for microrobotics applications}, author = {Cot, Am\'elie and Dejeu, J\'er\^ome and Lakard, Sophie and Rougeot, Patrick and Gauthier, Micha\"el}, year = {2013}, address = {Tokyo, Japan}, booktitle = {IEEE/RSJ International Conference on Intelligent Robots and Systems, IROS'13.}, month = {nov}, pages = {2065 - 2070}, url = {https://publiweb.femto-st.fr/tntnet/entries/5748/documents/author/data}, doi = {10.1109/IROS.2013.6696633}, organization = {IEEE} }
article - Analysis and specificities of adhesive forces between microscale and nanoscale
IEEE Transactions on Automation Science and Engineering (Volume 10, Issue (3), jul 2013, Pages :562 - 570)
Gauthier, Michaël | Alvo, Sébastien | Dejeu, Jérôme | Tamadazte, Brahim | Rougeot, Patrick | Régnier, Stéphane
pdf | doi

2012 (3)

article - Electrosynthesis and characterization of polymer films on silicon substrates for applications in micromanipulation.
Synthetic Metals (Volume 162, Issue (24), dec 2012, Pages :2370 - 2378)
Cot, Amélie | Lakard, Sophie | Dejeu, Jérôme | Rougeot, Patrick | Magnenet, Claire | Lakard, Boris | Gauthier, Michaël
pdf | doi
article - Nanostructured non-adhesive surfaces for Micro- and Nanomanipulation.
The Journal of Physical Chemistry C (Volume 116, 2012, Pages :15117-15125)
Dejeu, Jérôme | Bechelany, Mikhael | Berodier, Elise | Rougeot, Patrick | Michler, Johann | Gauthier, Michaël
pdf | doi
inproceedings - Control of Adhesion using Surface Functionalisations for Robotic Microhandling
Conference on Intelligent Robots and Systems. / Vilamoura, Algarve, Portugal (Publisher : IEEE, Volume sur CD ROM, 2012, Pages pages 2307-2312)
Dejeu, Jérôme | Rougeot, Patrick | Lakard, Sophie | Gauthier, Michaël
pdf | bibtex@inproceedings{dejeu:hal-00772424, title = {Control of Adhesion using Surface Functionalisations for Robotic Microhandling}, author = {Dejeu, J\'er\^ome and Rougeot, Patrick and Lakard, Sophie and Gauthier, Micha\"el}, year = {2012}, address = {Vilamoura, Algarve, Portugal}, booktitle = {Conference on Intelligent Robots and Systems.}, pages = {2307-2312}, url = {https://publiweb.femto-st.fr/tntnet/entries/1505/documents/author/data}, volume = {sur CD ROM}, publisher = {IEEE} }

2010 (5)

inproceedings - Development of a new nanotribometer with multi asperity contact.
NordTrib 2010 / Storforsen, Suède (2010, Pages pages 1-9)
Dejeu, Jérôme | Abadie, Joël | Piat, Emmanuel | Rougeot, Patrick | Oster, Stéphane | Stempflé, Philippe | Takadoum, Jamal
pdf | bibtex@inproceedings{dejeu:hal-00503945, title = {Development of a new nanotribometer with multi asperity contact.}, author = {Dejeu, J\'er\^ome and Abadie, Jo\"el and Piat, Emmanuel and Rougeot, Patrick and Oster, St\'ephane and Stempfl\'e, Philippe and Takadoum, Jamal}, year = {2010}, address = {Storforsen, Su\`ede}, booktitle = {NordTrib 2010}, month = {jun}, pages = {1-9}, url = {https://publiweb.femto-st.fr/tntnet/entries/1337/documents/author/data} }
inproceedings - Development of a New Nanotribometer with Multi Asperity Contact
(2010)
Dejeu, Jérôme | Abadie, Joël | Piat, Emmanuel | Rougeot, Patrick | Oster, Stéphane | Stempflé, Philippe | Takadoum, Jamal
pdf | bibtex@inproceedings{86c6fb13-f883-46b8-a0ee-d438b1022035, title = {Development of a New Nanotribometer with Multi Asperity Contact}, author = {Dejeu, J\'er\^ome and Abadie, Jo\"el and Piat, Emmanuel and Rougeot, Patrick and Oster, St\'ephane and Stempfl\'e, Philippe and Takadoum, Jamal}, year = {2010}, month = {jun}, url = {https://publiweb.femto-st.fr/tntnet/entries/10835/documents/author/data}, organization = {14th Nordic Symposium on Tribology} }
unpublished - GDR CNRS 3180 MECANO (jun 2010)
Dejeu, Jérôme | Gauthier, Michaël
bibtex@unpublished{61c4a54e-b19e-4124-b7cb-531f21ad28d0, title = {GDR CNRS 3180 MECANO}, author = {Dejeu, J\'er\^ome and Gauthier, Micha\"el}, year = {2010}, month = {jun} }
book - Films auto-assemblés de polyélectrolytes - Mécanisme de croissance et stabilité
Editions Universitaires Europeennes (EUE) (apr 2010, Pages 1 - 228)
Dejeu, Jérôme
pdf | bibtex@book{dejeu:hal-00486902, title = {Films auto-assembl\'es de poly\'electrolytes - M\'ecanisme de croissance et stabilit\'e }, author = {Dejeu, J\'er\^ome}, year = {2010}, month = {apr}, pages = {1 - 228}, url = {http://hal.archives-ouvertes.fr/hal-00486902}, publisher = {Editions Universitaires Europeennes (EUE)} }
inproceedings - Improvement of robotic micromanipulations using chemical functionalisations.
Precision Assembly Technologies and Systems. / Chamonix, France (Publisher : Theoretical Computer Science, Volume 1, 2010, Pages pages 215-221)
Dejeu, Jérôme | Rougeot, Patrick | Gauthier, Michaël | Boireau, Wilfrid
pdf | bibtex@inproceedings{dejeu:hal-00459455, title = {Improvement of robotic micromanipulations using chemical functionalisations.}, author = {Dejeu, J\'er\^ome and Rougeot, Patrick and Gauthier, Micha\"el and Boireau, Wilfrid}, year = {2010}, address = {Chamonix, France}, booktitle = {Precision Assembly Technologies and Systems.}, pages = {215-221}, url = {https://publiweb.femto-st.fr/tntnet/entries/1338/documents/author/data}, volume = {1}, publisher = {Theoretical Computer Science} }