Antoine CHAILLET : "Closed-loop approaches to deep brain stimulation for Parkinson's disease in the entrainment and pacemaker hypotheses"

You are all invited to join our AS2M seminar where Antoine Chaillet (https://l2s.centralesupelec.fr/en/u/chaillet-antoine/) will give a talk entitled : Closed-loop approaches to deep brain stimulation for Parkinson's disease in the entrainment and pacemaker hypotheses on Wednesday May 31st at 2.00 P.M

Abstract : Deep brain stimulation (DBS) has constituted an impressive scientific breakthrough in the treatment of Parkinson's disease. In clinical practice, this electrical stimulation is made in open loop, meaning that a fixed stimulation waveform is delivered to the patient at all times. The most recent stimulation devices now allow to both stimulate targeted regions of the brain and record their activity. These technological advances open the way to closed-loop approaches to DBS, in which the stimulation depends on the current state of the patient. So far, most developed closed-loop DBS strategies are "on-demand", meaning that a fixed stimulation waveform is delivered, but only if a given biomarker of the disease overpasses a certain threshold. The tools of control theory allow to go beyond such policies by adapting the stimulation waveform in real time, with the hope to deliver a more efficient, more respectful and less dispendious stimulation signal..[...]