TENURE TRACK POSITION : Micro-nanotechnologies for the production of biomedicine “on-chip”
Teaching activities
The candidate recruited at the Junior Professorship will be appointed to the ISIFC school, which offers an engineering program and an international master’s degree in biomedical engineering.
The recruited candidate will teach in French and English in the fields of electronics and/or applied physics dedicated to medical devices.
The candidate will be expected to develop high-level expertise and take the initiative in integrating environmental impact considerations into the design of medical devices. In conjunction with their research activities, she/he will provide strong support for the school’s multidisciplinary projects and help establish collaborative relationships with academic, hospital, and industry stakeholders in the medical device field.
Research activities
Inside the Institute of Technologies, The FEMTO-ST laboratory (https://www.femto-st.fr) is a CNRS UMLP joint research unit (UMR) emerging to CNRS-Ingénierie. It is one of the largest CNRS laboratory in France with 700 peoples. The laboratory’s strategy is based on five priorities, including Sciences and Technologies for Biology and Health, which is the main research topic of this CPJ. The recruited candidate will be based in the Micro Nano Sciences and Systems (MN2S) department of FEMTO-ST.
FEMTO-ST is internationally recognized as a center of excellence in micro-nanotechnologies for the detection, sorting, analysis and qualification of biological elements of interest for the production of biomedicines. This positioning is based on the scientific expertise of its research teams in microsystems, microfluidics, optics and acoustics, as well as on recognized expertise in physical chemistry and biochemistry. The CPJ will have dedicated access to the MIMENTO micro-nanofabrication and characterization technology center (https://www.femto-st.fr/fr/Plateformes-technologiques/Mimento-presentat…), a member of the French national RENATECH network. The CPJ will join and strengthen this international leadership position by providing skills in the online and on-chip qualification of biomedicines in synergy with the multidisciplinary expertise already present in the laboratory and in conjunction with health and biology laboratories from UMLP.
In an international context of innovation for biotherapy, the CPJ’s scientific project focuses on proposing new methods and original microsystems for the qualification (online or on a microfluidic chip) of acellular & cellular biomedicines. The systems could also enable the identification and trapping of potential contaminants in the production line.
The CPJ will propose the development of Lab-On-Chip, Organ-On-Chip and/or new analytical methods for bioanalysis, based on nano- and microtechnologies. Thus, the recruited person will be able to respond to scientific challenges such as:
(i) development and integration of microfluidic components, bio-microsensors and actuators within lab-on-chip and organ-on-chip type devices,
(ii) development of innovative microtransducers and the associated bio-interfaces for the quantification of rare biological elements in complex fluid,
(iii) new analytical methodologies based on engineered substrates for the multimodal and discriminative detection and nanocharacterization of biological or bioengineered objects,
(iv) microsystems allowing the elucidation of mechanisms of action, functions and interactions of objects such as: cells, vesicles or macromolecular complexes, directly in their bioproduction environment and/or in complex biofluids.
The candidate will develop an original research project on an international challenge, with the goal of submitting a proposal to the European Research Council (ERC). The candidate may base their projects on the current expertise of the MN2S department or on projects currently in the development or maturation phase within the MN2S department. The candidate will join one of the two teams listed below within the MN2S department, whose research areas are as follows:
Research axes within the BIND team:
- Online multiplexed acoustic biosensors
- Integration of sorting microdevices for the separation of biological elements in complex environments
- 3D models of microvessels, applications for tumor-on-chips in microphysiological systems.
- Integration of microsensors and microactuators into a lab-on-chip or organ-on-chip microfluidic system.
Research axes within the Nano2BIO team:
- Characterization of the composition-function relationship in complex biological solutions
- Development of nanovectors for theranostics.
- Hydrodynamic sorting of target nanoparticles, in-stream enrichment of target subpopulations.









