PhD position : Registration of 3D optical biopsies (application to medical imaging of high-resolution and wide field-of-view)
The scientific work concerns the development of accurate and robust registration methods between 3D visual information (optical biopsies). The PhD student will first focus on the development of calibration methods based on local visual features (e.g., geometric type information), matching methods, computing rigid transformations as well as reconstruction and mapping all the acquired data on the same final volume. This first work will provide a basis for extending these methods in aim to use global information such as pixel/voxel intensities, wavelet coefficients or any other global image information.
In addition, several parameters and external disturbances will be considered within this work such as physiological motion, … in order to limit potential artifacts.
This work will then be extended to non-rigid registration in which the observed tissue is subjected to a global (or a local minimum) deformation resulting, for instance, from the contact between the tissue and the imaging probe.